What I’ve Learned Over the Last 17 Years About Weathering Downturns

What I’ve Learned Over the Last 17 Years About Weathering Downturns

With the life sciences industry well into year five of a sustained downturn, one hot topic among leaders is how to survive difficult market conditions. It’s something I’ve thought a lot about as I launched Catalyst Advisors during the onset of the financial crisis in the spring of 2008.

The single most important thing I’ve learned about business resilience is the importance of perspective: learning quickly from mistakes, staying grounded in what matters, and viewing setbacks as opportunities. When things go south, you have to be ready to pivot to make it better: It sounds obvious, but it can be highly challenging to execute in the moment.

For me, over the past 17 years of running Catalyst Advisors, that perspective has been shaped (sometimes the hard way) in three main areas that I’ve found are so critical to the smooth functioning of a company: talent, culture, and strategic agility.

Marc de Garidel, CEO of Abivax, on the Best Leadership Advice He’s Given and Received

Marc de Garidel, CEO of Abivax, on the Best Leadership Advice He’s Given and Received

Abivax is a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to modulate the immune response in patients with chronic inflammatory diseases. Marc de Garidel, an experienced leader in the biopharma sector, was appointed CEO in 2023 to lead Abivax as it moves towards commercialization of its lead drug candidate, obefazimod, currently tested in phase 3 trials for the treatment of adults with moderately to severely active ulcerative colitis (UC). I recently talked with him about leadership and lessons he has learned over his career.